By Kar Neng Lai

ISBN-10: 9812838716

ISBN-13: 9789812838711

This guide presents functional and obtainable details on all points of normal nephrology, dialysis, and transplantation. It outlines present remedies in effortless language to assist readers comprehend the therapy purpose, and doesn't imagine vast wisdom of anatomy, biochemistry, or pathophysiology. inclusive of 33 chapters written via 31 specialists from 4 continents, this quantity covers all of the useful information within the emergency and long term administration of sufferers with electrolyte disturbance, acid-base disturbance, acute renal failure, universal glomerular illnesses, high blood pressure, pregnancy-related renal problems, continual renal failure, and renal alternative remedy. it really is therefore a vital resource of quickly reference for nephrologists, internists, renal fellows, and renal nursing experts, and is additionally compatible for graduate scholars and examine scientists within the box of kidney illnesses.

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Extra info for A Practical Manual of Renal Medicine: Nephrology, Dialysis and Transplantation

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Consequently, the lungs’ ability to compensate for metabolic acidosis is impaired. In addition, hypoxemia may lead to hyperventilation and respiratory alkalosis. With HCO3−-based dialysis, the dialysate compartment has a relatively high PCO2 (as high as 130 mmHg), generated by the addition of a small amount of acetic acid into the HCO3− solution. Excess CO2 diffuses through the dialysis membrane into the venous blood. With normal lungs, the excess CO2 is rapidly disposed of via ventilation; when ventilation is severely compromised, however, PCO2 may rise, leading to respiratory acidosis.

Salicylates stimulate the respiratory center in the medulla, leading to hyperventilation and respiratory alkalosis. It also leads to an increased production of lactic acid and ketoacids, resulting in metabolic acidosis. Salicylic acid itself only accounts for a few mmol/L of the total acids present. 3–1 mmol/kg/day. This is derived from: • sulfuric acid resulting from the metabolism of sulfur-containing amino acids such as cysteine, cystine, and methionine • phosphoric acid resulting from the metabolism of phosphoproteins and phosphoesters • H+ resulting from the metabolism of cationic amino acids such as lysine and arginine.

The equation does not carry a body weight variable because it normalizes GFR to body surface area. — It is most accurate in subjects with moderate chronic kidney disease (CKD) and less accurate at the extremes of GFR, underestimating at high GFR but overestimating with advanced CKD. g. 73 m2, with or without kidney damage. 79 (if female). qxd 10 6/2/2009 3:00 PM Page 10 S. C. W. 85 (if female). ) — The equation was developed in 1976 in 249 men with stable serum creatinine. — It is suitable only for patients with stable renal function.

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A Practical Manual of Renal Medicine: Nephrology, Dialysis and Transplantation by Kar Neng Lai


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